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国家重点研发方向

干细胞定向分化及细胞转分化   

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领域简介

干细胞异质性及命运决定的调控网络:干细胞早期分化中单细胞水平异质性及命运调控的关键机制。 原始生殖细胞发育和分化的调控:原始生殖细胞的关键调控因素及在生殖细胞特化过程中的作用。

发表论文

论文名称 刊物与发表年
Ci antagonizes Hippo signaling in the somatic cells of the ovary to drive germline stem cell differentiation. CELL RESEARCH
2015
Argonaute and Argonaute-Bound Small RNAs in Stem Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2016
Extracellular signal-regulated kinase signaling pathway regulates the endothelial differentiation of periodontal ligament stem cells CHINESE JOURNAL OF STOMATOLOGY
2016
Osteogenesis of adipose-derived stem cells on polycaprolactone-β-tricalcium phosphate scaffold fabricated via selective laser sintering and surface coating with collagen type I. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
2016
Biomaterial stiffness determines stem cell fate LIFE SCIENCES
2017
β-Cyclodextrin induces the differentiation of resident cardiac stem cells to cardiomyocytes through autophagy BIOCHIMICA ET BIOPHYSICA ACTA
2017
Reprogramming of Dermal Fibroblasts into Osteo-Chondrogenic Cells with Elevated Osteogenic Potency by Defined Transcription Factors STEM CELL REPORTS
2017
Molecular control of nitric oxide synthesis through eNOS and caveolin-1 interaction regulates osteogenic differentiation of adipose-derived stem cells by modulation of Wnt/β-catenin signaling STATISTICAL INFERENCE FOR STOCHASTIC PROCESSES
2016
Strategy for constructing vascularized adipose units in poly(l-glutamic acid) hydrogel porous scaffold through inducing in-situ formation of ASCs spheroids ACTA BIOMATERIALIA
2017
Semaphorin 4D Enhances Angiogenic Potential and Suppresses Osteo-/Odontogenic Differentiation of Human Dental Pulp Stem Cells. JOURNAL OF ENDODONTICS
2017

相关机构

中国科学院广州生物医药与健康研究院(简称“广州生物院”)是由中国科学院、广东省和广州市人民政府三方共建,从事干细胞与再生医学、化学生物学、感染与免疫、公共健康、科研装备研制等研发的科研机构,于2006年3月获中央机构编制委员会批准正式成立,是中国科学院第一个与地方共建、共管、共有的新型研发机构。广州生物院面向人类健康与“健康中国”战略,聚焦生命健康领域前沿重大科学问题和重要疾病机理,以建成国际一流...

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