干细胞领域知识发现平台

专家简介

Dr Shinya Yamanaka is a Japanese physician and researcher of adult stem cells. He serves as the director of Center for iPS Cell Research and Application and a professor at the Institute for Frontier Medical Sciences at Kyoto University. ; as a senior investigator at the UCSF-affiliated J David Gladstone Institutes in San Francisco, California; and as a professor of anatomy at University of California, San Francisos UCSF). Yamanaka is also the current president of the International Society for Stem Cell Research (ISSCR). He received the Wolf Prize in Medicine in 2011 with Rudolf Jaenisch , the Milennium Technology Prize in 2012 together with Linus Torvalds. In 2012 he and John Gurdon were awarded the Novel Prize for Physiology or Medicine for the discovery that mature cells can be converted to stem cells. In 2013 he was awarded the $3 million Breakthrough Prize in Lifesciences for his work.

发表论文

论文名称	刊物与发表年
Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway	THE EMBO JOURNAL 2000
Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice	STEM CELLS TRANSLATIONAL MEDICINE 2015
Identification and targeted disruption of the mouse gene encoding ESG1 (PH34/ECAT2/DPPA5)	BMC DEVELOPMENTAL BIOLOGY 2006
Differential Roles for Sox15 and Sox2 in Transcriptional Control in Mouse Embryonic Stem Cells	JOURNAL OF BIOLOGICAL CHEMISTRY 2005
Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells	BMC DEVELOPMENTAL BIOLOGY 2006
Reprogramming somatic cells towards pluripotency by defined factors.	CURRENT OPINION IN BIOTECHNOLOGY 2007
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation	GENES TO CELLS 2006
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation	GENES TO CELLS 2006
Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity	CELLSTEMCELL 2016
The	CELLSTEMCELL 2014

发表专利

专利名称	专利公开号
Nuclear reprogramming factor and induced pluripotent stem cells	US2009047263A1
METHOD OF EFFICIENTLY ESTABLISHING INDUCED PLURIPOTENT STEM CELLS	CA2695590A1
Efficient Method For Establishing Induced Pluripotent Stem Cells	WO_2015_056804_A1
Method For Improving Induced Pluripotent Stem Cell Generation Efficiency	WO_2011_090221_A1
Method For Screening Induced Pluripotent Stem Cells	WO_2011_087154_A1
Differentiated Cells Originating In Artificial Pluripotent Stem Cells	WO_2009_096049_A1
Method For Sorting Of Pluripotent Cells	WO_2013_103156_A1
Genes With Es Cell−specific Expression	WO_2002_097090_A1
Effective Nucleus Initialization Method	WO_2009_075119_A1
Nuclear Reprogramming Factor	WO_2007_069666_A1

研究方向

机构介绍

The Japanese name of the Institute for Frontier Medical Sciences is Saisei Ikagaku Kenkyujo, which means "Institute for Regenerative Medicine". It is currently the only institute in Japan bearing the name "saisei ikagaku (regenerative medicine)". It has approximately 150 staff members who conduct research on studies related to regenerative medicine, such as basic biology, stem cell biology, and engineering, as well as applied studies on regenerative medicine. Further, the institution provides education and research guidance to approximately 100 graduate students and research students every year. The institution has also been acknowledged as a joint usage/research center for regenerative medicine in order to operate as Japan's core research center for regenerative medicine. Its obligations are continually increasing. We strive in research and education together with the research staff for the development of regenerative medicine. We thank you for your continuing support.

专家资讯

参与项目