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Ward F Odenwald
One of the longstanding goals of neurobiologists is to describe, in molecular terms, how a neural progenitor cell (NPC) can generate an ordered series of uniquely fated neurons and glia. Recent studies reveal that many, or all, neural-subtype identities can be linked to sequentially changing regulatory programs within NPCs. Two new studies, in this issue of Developmental Cell , provide novel insights into the molecular details of how Drosophila NPCs transition from one offspring identity program to the next.
National Institutes of Health;Neural Cell-Fate Determinants Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 9000 Rockville Pike, MD 20892, USA.