干细胞领域知识发现平台

提升科研信息化水平
支撑研究所科技创新

  融合多源信息    打通数据孤岛
  挖掘知识关联    放大数据价值
  集成知识计算    促进知识发现

免费注册账号
查看全文和研发动态、知识导航以及收藏您喜欢的数据等操作,您需要注册一个免费帐户并登录。

写笔记

您最近的笔记
Neural stem/precursor cells for the treatment of ischemic stroke.
Journal of the neurological sciences, Issue: 1-2, Volume: 265, Pages: 73-77. | 2008-02-15
0 Patent citations    58 Scholarly citations     Reference Count: 0
Marco Bacigaluppi

摘要

In ischemic stroke, the third most frequent cause of mortality in industrialized countries, therapeutic options have until now been limited to the first hours after disease onset. Cell transplantation has emerged in various neurological disorders, including experimental stroke, as a successful recovery-promoting approach also in the post-acute stroke phase. However, before envisaging any translation into humans of such promising cell-based approaches we still need to clarify: (i) the ideal cell source for transplantation, (ii) the most appropriate route of cell administration, and, last but not least, (iii) the best approach to achieve an appropriate and functional integration of transplanted cells into the host tissue. Here we discuss, with special emphasis on neural stem/precursor cells, potential mechanisms that may be involved in the action of cell-based therapies in stroke.


机构

Department of Neurology, University Hospital Zurich (USZ), Frauenklinikstr, 26, CH-8091 Zurich, Switzerland.


实验动物:

mouse(小鼠)    monkey(猴子)    gerbil(沙鼠)   

科学仪器:

生物芯片   

细胞器官:

neural precursor cell   

方法技术:

cell transplantation   

实验方案:

MTT Assay Protocols(MTT检验方案)   

文献类型:

journal article;review;

出版商:

Elsevier

发表时间:

2008-02-15

基金信息